Zeaxanthin and Lutein in the Management of Eye Diseases.
نویسندگان
چکیده
1 Institute of Medicine, Chung Shan Medical University, Taichung 40256, Taiwan 2Department of Medical Research, Chung Shan Medical University Hospital, Taichung 40256, Taiwan 3Department of Natural Sciences, Fordham University, New York, NY 10458, USA 4Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China 5Department of Ophthalmology, College of Medicine, University of Florida, FL 32610, USA 6Department of Biophysics, Faculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University in Krakow, 31-007 Krakow, Poland
منابع مشابه
Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies?
Zeaxanthin and lutein are two carotenoid pigments that concentrated in the retina, especially in the macula. The effects of lutein and zeaxanthin on the prevention and treatment of various eye diseases, including age-related macular degeneration, diabetic retinopathy and cataract, ischemic/hypoxia induced retinopathy, light damage of the retina, retinitis pigmentosa, retinal detachment, and uve...
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Lutein and zeaxanthin, two carotenoid pigments of the xanthophyll subclass, are present in high concentrations in the retina, especially in the macula. They work as a filter protecting the macula from blue light and also as a resident antioxidant and free radical scavenger to reduce oxidative stress-induced damage. Many observational and interventional studies have suggested that lutein and zea...
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The effects of lutein and zeaxanthin on lipopolysaccharide- (LPS-) induced secretion of IL-8 by uveal melanocytes (UM) were tested in cultured human UM. MTT assay revealed that LPS (0.01-1 μg/mL) and lutein and zeaxanthin (1-10 μM) did not influence the cell viability of cultured UM. LPS caused a dose-dependent increase of secretion of IL-8 by cultured UM. Lutein and zeaxanthin did not affect t...
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The lens and retina of the human eye are exposed constantly to light and oxygen. In situ phototransduction and oxidative phosphorylation within photoreceptors produces a high level of phototoxic and oxidative related stress. Within the eye, the carotenoids lutein and zeaxanthin are present in high concentrations in contrast to other human tissues. We discuss the role of lutein and zeaxanthin in...
متن کاملRole of lutein and zeaxanthin in visual and cognitive function throughout the lifespan.
The relationship between lutein and zeaxanthin and visual and cognitive health throughout the lifespan is compelling. There is a variety of evidence to support a role for lutein and zeaxanthin in vision. Lutein's role in cognition has only recently been considered. Lutein and its isomer, zeaxanthin, are taken up selectively into eye tissue. Lutein is the predominant carotenoid in human brain ti...
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عنوان ژورنال:
- Journal of ophthalmology
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016